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Abstract: Chronic exposure to ultraviolet B (UVB) irradiation is a major cause for skin photoaging
Traditionally GLP-1(9-36) was considered inactive, however more recent studies indicate that GLP-1(9-36) can contribute to inhibiting glucagon secretion by inhibiting voltage-gated calcium channels through a GPCR mechanism, an effect which reduces the number of glucagon containing vesicles that are available for exocytosis, thereby contributing the the decrease in glucagon secretion (Figure 1)(Zheng et al, 2024)
(PubMed) Lee BJ, Huang MC, Chung LJ, et al
However, medication alone is not the entire solution
The spindle cells show no nuclear atypia and no mitotic activity is appreciated
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